? ?? ?? ?? Many people are suffering from hyperuricemia, after the use of uric acid down, the symptoms of joint pain has not improved but aggravated, do you know why this is? The reporter invited Professor Sun Erwei of the Department of Rheumatology and Immunology of the Third Affiliated Hospital of Southern Medical University to speak for you.
? ?? ?? ?? As we all know, the cause of gout is very clear, that is, the body uric acid is too high beyond the human body can afford to form crystallization, deposited in the joints, skin, blood vessels and other parts of the body, stimulate the body to clean up the bacterial macrophages and neutrophils, release the body tissue swelling red, fever pain small molecules, that is, an inflammatory reaction. But uric acid crystallization is not bacteria, macrophages and neutrophils are powerless to this inflammation, they can only help more and more, leading to inflammation aggravated. So gout patients in the acute attack period that is quite painful.
? ?? ?? ?? To get rid of uric acid, the body has to rely on its kidneys. But the kidney's ability to exercise is limited, and it removes only uric acid from the blood, which is as long as the uric acid deposited in tissues, muscles, blood vessels and, in particular, joints. A large amount of uric acid accumulates in the body for a long time, to go back to the blood circulation, and then removed by the kidney, is a long process. Too much uric acid is not removed in time to form crystalline salts in the tissue.
? ?? ?? ?? When the symptoms are mild, the body resists itself and initiates an anti-inflammatory response, which allows it to relieve itself after a few days, but the problem of excessive uric acid has not been solved. If you take your medicine when it hurts, forget it when you're scarred, and continue to drink and eat meat, gout becomes more frequent and joints become more painful each time.
? ?? ?? ?? Therefore, gout is only a superficial phenomenon, and high uric acid in the body is the root cause of the disease. Pain relief is necessary, but only by reducing uric acid to normal levels can gout be fundamentally avoided.
? ?? ?? ?? In this case, why so many clinical \"pain friends \", uric acid down, joint pain has not been relieved but even more? The key problem, says mr sun, is that uric acid doesn't fall as fast as possible.
? ?? ?? ?? In general, drugs work through the blood. For patients with long-term hyperuricemia, when the uric acid in the blood is reduced, the large amount of uric acid deposited in the whole body tissues, such as muscles, skin, blood vessels, organs, bones and so on, will be transferred to the blood, and it is easy to break the balance of urea concentration in the joint, thus making the crystallization more easy to produce, thus inducing the attack of acute gout, resulting in pain is difficult to bear.
? ?? ?? ?? How to quietly reduce uric acid to the invisible without breaking the balance is almost an art. So it's not painful when you take some anti-inflammatory drugs, and then take some acid medicine can be. It's still under the doctor's command.
? ?? ?? ?? Not all people with elevated blood uric acid have symptoms of joint pain, Sun cautioned. Many people have found that blood uric acid exceeds the standard, even higher and higher, medically known as hyperuricemia. Of the 100 patients with hyperuricemia, only about 10 have gout. Many people don't take elevated blood uric acid seriously because they don't have gout, don't treat it and don't control their diet.
? ?? ?? ?? But after all, uric acid is a metabolic waste that, if deposited in the kidney for a long period of time, crystals or even stones form here, which can lead to impaired kidney function and affect the excretion of other metabolites in the body.
? ?? ?? ?? High uric acid may also destroy islet cell function and induce diabetes. It is also a high risk factor for cardiovascular events such as hypertension, coronary heart disease, myocardial infarction and cerebral infarction. In other words, uric acid crystals deposit in joints, causing joint swelling and pain, and may also deposit in other organs of the body, quietly causing more damage, except that there may be no obvious symptoms of discomfort in the early stages. So if you start having joint pain, it's the body that warns you that excessive uric acid has begun to destroy the joints, and that you may need to check further to see if other organs are affected by it. (Media Reporter Zhou Jieying Correspondent Yu Hualing)